Tuesday, June 25, 2013

Beginning to learn to read MRI

As a radiology student or practitioner you must often have felt intrigued about MRI. And always wanted to start learning mri interpretation at some point.So this is a small step towards it.

THE PRINCIPLE........
Just trying to make things too simple....
Xray, USG or CT scans seem much more simpler since they have one or only few different methods of looking at things.Like USG means grey scale... doppler , CT--plain, contrast.
MRI however seems to be more complex since there are various  ways you are looking at the same anatomy and at times different ways of looking at different structures ..where starts all the PROBLEMS and COMPLEXITY. It is just like looking at same thing with different coloured glasses causing all the confusion.

THE PHYSICS

Hearing about it you will often feel like losing the race before you have started it....It is like an ocean. But still u cant escape physics.It makes sense to know at least some basics whats happening in MRI.

In most simple way-
Everything boils down to PROTONS (H) which is there in abundance in body.This is where the MAGNETISM starts off....... becos these every individual protons also are tiny magnets. They get aligned some thing like...... straight  when placed in a magnet i.e. the huge round machine you see with restricted entry and large CAUTION board on the door.

There is another thing here which is called the RADIOFREQUENCY waves.It comes from an external source which is transmitted to body. What do they do after all ? They bring about SOME change in the magnetic field in these PROTONS.

This SOME change gives out  what is called a SIGNAL. This SIGNAL is captured by the receiver coils which you see wrapped around the body part being scanned..

This SIGNAL then undergoes what is called as FOURIER TRANSFORMATION.........  some complex mathematics  (dont worry abt it for now) which gives the final image which we see on the screen. The entire thing is much more complex though.

Feels like some WONDER or MAGIC...Interactions of  magnets and radiofrequency one is able to see in great detail the internal human anatomy.



SOME MORE BASICS


        After a short cut through PHYSICS lets get into looking into MRI proper.....

T1,T2,STIR,PD,CISS,SPGR,FLAIR,GRE. ??? ##^^%!!@@%%%
....................oops looks like suddenly  in the middle of a sea.
At this point forget the rest and just hold on to T1 and T2  so that u dont drown down...  and if u have some more strength also hold on to FLAIR and STIR.......these are supposedly very basic  things.......getting u just above water.

Now this comes with a price...the TR and TE which are fundamental. These are which make the SEQUENCES. You can get away without these but better to know these becos sooner or later u r going to get stumped by them.  Earlier you learnt that RF is transmitted to body which then gives out a SIGNAL.  So....

TR is time between two RF pulses.
TE time between RF pulse and signal.
In simple terms manipulation of these parameters gives different sequences.like...

T1- short TR short TE
T2- long TR long TE

Another one add here...........PD (proton density)-long TR and short TE.

A typical spin echo sequence would look like

90            180        echo      90



Now along with TR and TE, there is also TI (time to inversion). TI comes into play in inversion recovery sequences like FLAIR and STIR.It is time between 180 pulse and 90.
What do the Inversion recovery  seqs do ?
In simple words it is suppression of some things to be able to make other things more prominent.Example Fat is nulled in STIR and CSF is nulled in FLAIR.
Inversion recovery would look like

180         90          180
          TI

Its quite interesting  to see that  different type of images are obtained by changing TR and TE which are like the backbone these pulse sequences.

A WORD ABOUT GRADIENT SEQUENCES

In simple words traditional spin echo is time consuming. Rephasing of magnetisation is by RF. Whereas   Gradient seqs  are fast ! and rephasing is done by gradients.



THE CORE PHYSICS
This sequence of events are seen in a typical spin echo sequence.



Monday, June 24, 2013

GOING AHEAD OF T1 and T2

After seeing the basic sequences we go another step forward


FLAIR and STIR  make the pathology look quite obvious and staring. FLAIR in brain suppresses CSF , STIR supressed Fat .
FLAIR is T2 minus CSF.
FLAIR cor brain dark CSF and dark white matter
















STIR coronal ALL FAT is suppressed

PROTON DENSITY PD

Used mainly in musculoskeletal. For cartilage and meniscus evaluation.



PD with fat sat -menisci and cartilge
PD Look at traingular dark menisci and cartilage rim   
BRAIN DIFFUSION and ADC   commonly done in stroke

DIFFUSION

ADC

 BRAIN SPACE axial Heavily T2 weighted
 

Look for cochlea and 7th, 8th nerves

IDENTIFYING THE SEQUENCES




After all the super short physics we come to seeing MRI.   So first begin with identifying the sequences.

T2 CSF is bright  
Starting with SPINE 
T1 CSF is dark

BRAIN  
BRAIN T1 CSF is dark White M-white greyM-grey

BRAIN T2 CSF is bright, White M -dark,grey M- grey



  

KNEE--look at   fluid in joint is bright on T2 and dark on T1.

T1
 
T2 fluid bright in suprapatellar bursa





PELVIS look at bladder fluid dark on T1 and bright on T2.


T2 Sag PELVIS  Bright bladder



T1 axial  Bladder dark

ABDOMEN 

T2 Fat sat fluid in GB


SOME MORE SEQUENCES

Now we see some some common sequences how they look.


PDFS axial showing labrum

PDFS coronal Shoulder showing supraspinatus tendon 




SWI brain  showing the dark BLEED.








               MRVenogram 3D TOF for thrombosis

MR angio Brain 3DTOF



SPACE axial look for 7th,8th nerves and cochlea
MRCP HASTE coronal (heavily T2 weighted) fluid filled structures look bright.

                                                  MRCP HASTE axial


SOME COMMON CONDITIONS

Lets see some common abnormalities how they appear on MRI.

INFARCT

Axial T2 mild hyperintense lesion in right periventricular region. CSF signal lesion on left side.

Axial T1- right side mildly hypointense . left CSF signal

FLAIR Coronal hyperintense signal on right

Diffusion restriction on right side- fresh infarct. No restriction left-old infarct.

Decreased ADC on right- fresh infarct. Increased on left-old infarct.


MCA Territory infarct

T2 axial 

T2 axial left fronto parietal hyperintensity

T1 axial hypointensity

FLAIR coronal

Diffusion restriction